Hyperinsulinemia adversely affects lung structure and function

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Hyperinsulinemia adversely affects lung structure and function.

There is limited knowledge regarding the consequences of hyperinsulinemia on the lung. Given the increasing prevalence of obesity, insulin resistance, and epidemiological associations with asthma, this is a critical lacuna, more so with inhaled insulin on the horizon. Here, we demonstrate that insulin can adversely affect respiratory health. Insulin treatment (1 μg/ml) significantly (P < 0.05) ...

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ژورنال

عنوان ژورنال: American Journal of Physiology-Lung Cellular and Molecular Physiology

سال: 2016

ISSN: 1040-0605,1522-1504

DOI: 10.1152/ajplung.00091.2015